Cell model of the brain provides new knowledge on developmental disease
PhD scholar Mansoureh Shahsavani and docent Anna Falk on the Division of Neuroscience. Credit score: Stefan Zimmerman By reprogramming pores and skin cells into nerve cells, researchers at Karolinska Institutet are creating cell fashions of the human mind. In a brand new examine printed in Molecular Psychiatry the researchers describe how cells from sufferers with the extreme developmental illness lissencephaly differ from wholesome cells. The tactic can present very important new information on difficult-to-study congenital ailments. Lissencephaly is a uncommon congenital developmental illness that may be brought on by, amongst different anomalies, a mutation of the DCX gene. Affected people are born with severe developmental disabilities and a mind t...